Can ibuprofen increase blood pressure

High blood pressure and women. Updated October 31, Antidepressant drugs effects on blood pressure. Front Cardiovasc Med. Published Aug 3. Understanding over-the-counter OTC medications and high blood pressure. Updated November 30, Centers for Disease Control and Prevention. High blood pressure symptoms and causes.

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Antidepressant Drugs. But they can lead to dangerously high blood pressure when combined with: Aged and fermented foods e. Summary Drugs that increase blood pressure either constrict blood vessels, increase fluid retention, or raise hormone levels. What are normal blood pressure numbers?

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Is Lisinopril a Diuretic? How to Lower Systolic Blood Pressure. How Hypertension Is Treated. There was no statistically significant effect on blood pressure. In a trial of 18, patients with hypertension, participants were randomized to receive aspirin 75 mg daily or placebo for a mean of 3. A systematic review identified 32 randomized controlled trials RCTs that included 3, patients who were treated for at least four weeks with nonselective NSAIDs.

Most studies enrolled patients with osteoarthritis or rheumatoid arthritis, although some included patients with other conditions. Patients who received ibuprofen had a greater incidence of new hypertension compared with those in the control group 2. A meta-analysis of 19 RCTs that included 45, patients with arthritis evaluated blood pressure after more than four weeks of treatment with cyclooxygenase-2 inhibitors, nonselective NSAIDs, or placebo 5 Table 1 1 , 5 — 7. Another meta-analysis that included 49 RCTs with , patients—most of whom had arthritis—evaluated the effects of these agents on the diagnosis of hypertension after more than four weeks of treatment.

The study did not report absolute risk changes or provide numbers needed to treat or harm. Enlarge Print. Information from references 1 , and 5 through 7. A meta-analysis compared the cardiovascular safety of naproxen, ibuprofen, diclofenac, and celecoxib.

None of the drugs significantly increased the risk of myocardial infarction. Ibuprofen, naproxen, and celecoxib had no significant effect on the total cardiovascular death rate or all-cause mortality.

Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. Reprints are not available from the authors. A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure. Twenty-four-hour blood pressure monitoring and hour urine collection for prostaglandin E2, creatinine, and sodium were performed on days 1 and 8 of each study week.

Tablet counts and a 40 percent reduction in urinary prostaglandin E2 documented compliance with ibuprofen. Ibuprofen had no significant effect on systolic or diastolic blood pressure at any hour during the hour period.